Fractional-Order Modeling of Heat and Moisture Transfer in Anisotropic Materials Using a Physics-Informed Neural Network.

Mathematical models of heat and moisture transfer for anisotropic materials, based on the use of the fractional calculus of integro-differentiation, are considered because such two-factor fractal models have not been proposed in the literature so far. The numerical implementation of mathematical models for determining changes in heat exchange and moisture exchange is based on the adaptation of the fractal neural network method, grounded in the physics of processes. A fractal physics-informed neural network architecture with a decoupled structure is proposed, based on loss functions informed by the physical process under study.

Polymorphism of Carbamazepine Pharmaceutical Cocrystal: Structural Analysis and Solubility Performance.

Polymorphism is a common phenomenon among single- and multicomponent molecular crystals that has a significant impact on the contemporary drug development process. A new polymorphic form of the drug carbamazepine (CBZ) cocrystal with methylparaben (MePRB) in a 1:1 molar ratio as well as the drug's channel-like cocrystal containing highly disordered coformer molecules have been obtained and characterized in this work using various analytical methods, including thermal analysis, Raman spectroscopy, and single-crystal and high-resolution synchrotron powder X-ray diffraction. Structural analysis of the solid forms revealed a close resemblance between novel form II and previously reported form I of the [CBZ + MePRB] (1:1) cocrystal in terms of hydrogen bond networks and overall packing arrangements.

Material's Strength Analysis of the Coupling Node of Axle of the Truck Trailer.

Road transport plays an important role in the transport of goods and people and is important for the national economy. Damage usually excludes the means of transport from operation, which causes disruption of supply chains. One such damage is the failure of the suspension system of the vehicle or trailer, which usually occurs when the vehicle is heavily loaded.

Virtual Screening, Structural Analysis, and Formation Thermodynamics of Carbamazepine Cocrystals.

In this study, the existing set of carbamazepine (CBZ) cocrystals was extended through the successful combination of the drug with the positional isomers of acetamidobenzoic acid. The structural and energetic features of the CBZ cocrystals with 3- and 4-acetamidobenzoic acids were elucidated via single-crystal X-ray diffraction followed by QTAIMC analysis. The ability of three fundamentally different virtual screening methods to predict the correct cocrystallization outcome for CBZ was assessed based on the new experimental results obtained in this study and data available in the literature.

Analysis of the Vehicle Chassis Axle Fractures.

With the rapid development of the road transport industry, trucks with semi-trailers have become the main means of transporting goods by road. High quality, durability and reliability of the construction are the main requirements for the production of trailers. Trailer and semi-trailer axles are one of the main and most important components of a truck.