Assessment of cerebral oxygenation during repeated squat stands following an acute sport-related concussion (SRC) has the potential to identify physiological changes following SRC. All varsity university athletes completed a pre-season assessment and 53 were followed up within 5-days of suffering an SRC. Of the 53 participants, 29 had continuous beat-to-beat blood pressure (BP; sampled at 200 hz) collected by finger photoplethysmography, and 53 had right prefrontal cortex oxygenation collected by near-infrared spectroscopy (NIRS; sampled at 10 hz).
View Article and Find Full Text PDFBackground: Cannabinoids such as cannabidiol (CBD) exhibit anti-inflammatory properties and have the potential to act as a therapeutic following mild traumatic brain injury. There is limited evidence available on the pharmacological, physiological and psychological effects of escalating CBD dosages in a healthy, male, university athlete population. Furthermore, no dosing regimen for CBD is available with implications of improving physiological function.
View Article and Find Full Text PDFSport-related concussion (SRC) is known to disrupt neurohemodynamic activity, cardiac function, and blood pressure (BP) autoregulation. This study aims to observe changes in cerebrovascular and cardiovascular responses during controlled respiration after sustaining an SRC. University varsity athletes ( = 81) completed a preseason physiological assessment and were followed up within 5 days of sustaining an SRC.
View Article and Find Full Text PDFAnemia is a common symptom of hematological malignancies and red blood cell (RBC) transfusion is the primary supportive treatment, with many patients becoming transfusion dependent. Hemanext Inc. (Lexington, MA, United States) has developed a CE mark certified device to process and store RBCs hypoxically - citrate-phosphatedextrose (CPD)/phosphate-adenine-glucose-guanosine-saline-mannitol (PAGGSM) RBCs, leukocytes-reduced (LR), O/CO reduced - with the aim of improving RBC quality for transfusion.
View Article and Find Full Text PDFHeart rate variability (HRV), systolic blood pressure variability (BPV), and spontaneous baroreflex sensitivity (BRS) are indirect and approximate measures of autonomic regulation of the cardiovascular system. Studies have shown differences in HRV and BRS between males and females; however, no study has observed differences in BPV, HRV, or BRS between male and female athletes. One hundred males (age 21.
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