Publications by authors named "K Diserens"
This study reports two cases of Global Rostral Midbrain Syndrome (GRMS) and corpus callosum infarction in the context of shunt overdrainage caused by obstructive hydrocephalus due to aqueductal stenosis. We detail how thorough clinical evaluation and appropriate investigation helped avoid a coma misdiagnosis and describe the excellent response to pharmacological treatment and successful neurorehabilitation in both cases. We analyze the cognitive profile of patients with GRMS, a rare condition that mimics disorders such as coma and progressive supranuclear palsy at various stages.
View Article and Find Full Text PDFThe aim of this prospective, observational cohort study was to investigate and assess diverse neuroimaging biomarkers to predict patients' neurological recovery after coma. 32 patients (18-76 years, M = 44.8, SD = 17.
View Article and Find Full Text PDFArticle Synopsis
- People with rare neurological diseases (RNDs) often experience movement disorders, and a multidisciplinary rehabilitation approach, including telemedicine, can enhance treatment consistency and personalization.
- A scoping review was conducted to analyze available literature on telerehabilitation and teleassessment interventions for movement disorders in RNDs, resulting in 18 relevant studies focusing on various technologies like wearable sensors and virtual reality.
- Key findings indicated positive effects on gait, balance, and limb disability, but limitations such as small sample sizes and lack of standardized protocols were noted, highlighting the need for more rigorous research to improve remote rehabilitation and patient quality of life.
Background: We developed a gap analysis that examines the role of brain-computer interfaces (BCI) in patients with disorders of consciousness (DoC), focusing on their assessment, establishment of communication, and engagement with their environment.
Methods: The Curing Coma Campaign convened a Coma Science work group that included 16 clinicians and neuroscientists with expertise in DoC. The work group met online biweekly and performed a gap analysis of the primary question.
Background: Salivary cortisol is a safe and non-invasive measure of hypothalamic-pituitary-adrenal axis function and is used as a biomarker of the human stress response. Natural environments are recognized to contribute to help reduce the effect of stress.
Objective: To determine the feasibility of a salivary cortisol collection protocol for acute severely brain-injured patients, and to explore the influence of exposure to natural settings on salivary cortisol concentration as an index of stress level.