Publications by authors named "K Dhana"
Article Synopsis
- This study explored the connection between blood pressure variability (BPV) and cognitive function in older adults, particularly focusing on those over 65 years old.
- Researchers analyzed data from 4,770 participants from the Chicago Health and Aging Project, measuring blood pressure every three years and assessing cognitive abilities through standardized tests.
- Results indicated that higher BPV was linked to lower cognitive scores, especially among older Black adults, suggesting that fluctuations in blood pressure could contribute to cognitive decline as people age.
Background: Evidence suggests that long-term exposure to air pollution may increase the risk of dementia and related cognitive outcomes. A major source of air pollution is automotive traffic, which is modifiable by technological and regulatory interventions.
Objectives: We examined associations of four traffic-related air pollutants with rates of cognitive decline in a cohort of older adults.
Article Synopsis
- - Individuals with subjective memory complaints (SMCs) have higher levels of neurodegeneration biomarkers like neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP), indicating increased neurodegenerative processes.
- - The study involved 1,096 older adults and found that those with more memory complaints experienced a 12% increase in NfL and a 9.4% increase in GFAP compared to those with fewer complaints.
- - Participants reporting more memory issues also showed a faster cognitive decline, suggesting that SMCs could help identify individuals at higher risk for neurodegenerative conditions.
Article Synopsis
- This study investigates the impact of beverage consumption during adolescence on the risk of developing type 2 diabetes (T2DM) in adulthood, using a cohort of 41,317 women from the Nurses' Health Study II.
- It found that higher intake of coffee and orange juice in adolescence was linked to a lower risk of T2DM, while regular soda and iced tea consumption was associated with a higher risk.
- Changes in beverage habits from adolescence to adulthood also influenced T2DM risk, with increased coffee intake reducing risk and increased regular soda consumption elevating it.
Introduction: It is unclear whether inflammation, that is, high interleukin-6 (IL-6) levels, and genetic risk, that is, apolipoprotein E () ε4 allele, have a compounding effect on cognitive decline (CD).
Methods: We analyzed a subset of participants from the longitudinal cohort study, Chicago Health and Aging Project, comprising 1120 biracial community-dwelling older adults (60% Black and 62% women), and mean follow-up = 6.4 years.