Publications by authors named "K Demirkan"
Article Synopsis
- Voriconazole (VCZ) serum concentrations can be influenced by various factors, and this study explores its levels in patients with COVID-19-associated aspergillosis (CAPA) and invasive pulmonary aspergillosis (IPA).
- The study included 85 patients, finding that about 50.6% had VCZ levels in the therapeutic range, while a significant number had either sub-therapeutic or supra-therapeutic levels, with inflammation markers notably higher in those with supra-therapeutic levels.
- CAPA patients showed a higher incidence of adverse effects and elevated VCZ levels compared to IPA patients, highlighting the need for more frequent monitoring of VCZ in this group.
Objectives: Dyslipidemia is a well-established risk factor for atherosclerotic cardiovascular disease (ASCVD). ASCVD prevalence among people living with HIV (PLWH) is twice that of the general population. This study aimed to evaluate the infectious diseases (ID) physicians' attitudes on dyslipidemia management in PLWH.
View Article and Find Full Text PDFBackground: For hospitalized adults, it is important to initiate the early reintroduction of oral food in accordance with nutrition support team guidelines. The aim of this study was to develop and validate a machine learning-based algorithm that predicts the early termination of medical nutritional therapy (the transition to oral feeding).
Methods: This retrospective cohort study included consecutive adult patients admitted to the Hacettepe hospital (from 1 January 2018 to 31 December 2022).
There is little evidence of antimicrobial elimination via therapeutic plasma exchange (TPE) and no guidelines for antimicrobial optimal dosing in patients undergoing TPE. We aimed to assess current practices and knowledge regarding antimicrobial management during TPE. A structured online survey was conducted from May to November 2023, and physicians were invited to participate through national scientific platforms and professional societies.
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