Publications by authors named "K De Bock"
Aging is accompanied by a decline in neovascularization potential and increased susceptibility to ischemic injury. Here, we confirm the age-related impaired neovascularization following ischemic leg injury and impaired angiogenesis. The age-related deficits in angiogenesis arose primarily from diminished EC proliferation capacity, but not migration or VEGF sensitivity.
View Article and Find Full Text PDFBackground: Hip osteoarthritis patients display higher levels of fatty infiltration (FI) in the gluteus minimus (GM) compared to other hip muscles. We investigated specific histological factors such as fiber type composition and collagen deposition, and functional outcomes like muscle strength and activation associated with FI in these patients.
Methods: In twelve men (67 ± 6 y) undergoing total hip replacement (THR), hip and knee muscle strength and activation (electromyography, EMG) were assessed bilaterally.
Surgical treatments are promising for the treatment of lymphedema. It is important for patients, healthcare providers, and lymphedema community to understand that surgical treatments currently are not a cure for lymphedema but have provided promising options for patients. Post-operative care for patients following surgical treatment of lymphedema is vital to optimize and sustain patient outcomes.
View Article and Find Full Text PDFArticle Synopsis
- The development of intranasal vaccines for respiratory viruses is increasing, but currently only a live-attenuated influenza vaccine is approved for this method in the U.S.
- This study focused on the influenza virus and explored a novel structure of hemagglutinin (HA) called spike nanobicelles (SNB), which are lipid disc complexes that may enhance immune response.
- Using these SNBs, researchers found that intranasal immunization led to the production of broad-spectrum antibodies and protection against various strains of H1N1, potentially paving the way for more effective universal influenza vaccines.