Publications by authors named "K Da Costa"
Objective: to analyze the association between participation in training activities and the adherence to and use of personal protective equipment by workers and professionals involved in Health Residency Programs in Primary Health Care during the COVID-19 pandemic.
Methods: a cross-sectional study in Brazil between August/2020 and March/2021. We utilized the EPI-APS COVID-19 instrument and its adapted version for resident professionals.
Cue reactivity is the maladaptive neurobiological and behavioral response upon exposure to drug cues and is a major driver of relapse. A widely accepted assumption is that drugs of abuse result in disparate dopamine responses to cues that predict drug vs. natural rewards.
View Article and Find Full Text PDFGlioblastoma (GBM) is a malignant brain tumor with diffuse infiltration. Here, we demonstrate how GBM cells usurp guidance receptor Plexin-B2 for confined migration through restricted space. Using live-cell imaging to track GBM cells negotiating microchannels, we reveal endocytic vesicle accumulation at cell front and filamentous actin assembly at cell rear in a polarized manner.
View Article and Find Full Text PDFMinimal Change Disease and Focal Segmental Glomerulosclerosis are associated with good kidney prognosis and Thrombotic Microangiopathy with poor kidney survival in patients with COVID-19-associated nephropathies.
Am J Nephrol
December 2024
Article Synopsis
- * Among 94 patients, most were male and half had a history of hypertension; commonly observed kidney issues included collapsing glomerulopathy (CG), focal segmental glomerulosclerosis (FSGS), and thrombotic microangiopathy (TMA).
- * Results indicated that FSGS and minimal change disease (MCD) were linked to better kidney survival compared to TMA, underscoring differences in kidney complications resulting from COVID-19 within this patient group.
PFAS surveillance within a highly militarized island: a case study of Okinawa, Japan.
Environ Sci Process Impacts
December 2024
Article Synopsis
- PFAS are a group of over 12,000 synthetic chemicals commonly found in industrial, consumer, and food packaging products, raising environmental concerns due to their persistence.
- The study conducted on Okinawa Island, where U.S. military activities might contribute to PFAS contamination, involved sampling surface water at 61 locations to assess PFAS presence.
- Results revealed the detection of 15 different PFAS compounds, with varying concentrations across locations, highlighting significant pollution "hotspots" and indicating multiple sources of contamination in the region.