The impact of vascular injuries on the management of bile duct injury following laparoscopic cholecystectomy- insights from a prospective study.

Background: Our study aimed to compare the clinical presentation and outcomes of post-cholecystectomy bile duct injuries (BDI) with and without arterial injuries.

Methods: A prospective analysis of 123 patients with post-cholecystectomy BDI between July 2018 and January 2022 was performed. Multivariate logistic regression analysis was used to assess the impact of vascular injuries on perioperative complications and long-term outcomes after delayed repair.

COVID-19 vaccination and neurological complications: A cross-sectional observational study from a tertiary care centre of North India.

Vaccine hesitancy, anti-Vax campaigners and misinformation hound the administration of vaccines. Our study, conducted at Malwa region of the Punjab, India, was systematically carried out to look for adverse neurological effects after COVID-19 vaccination, given to 1000 people (>18 years and <60 years) who had received either single or multiple doses. No major neurological complications were found; the only side-effect was a transitory headache in 15% of the participants.

Laparoscopic-assisted pancreaticoduodenectomy for periampullary carcinoma: An experience of 50 cases from a single tertiary care center.

Objectives: Laparoscopic-assisted pancreaticoduodenectomy (LAPD) is being performed in several centers worldwide. The proportion of minimally invasive pancreaticoduodenectomy for periampullary carcinoma (PAC) has recently increased, owing to its potential benefits. However, the safety and feasibility of LAPD have not yet been standardized.

Gold-Graphene Quantum Dot Hybrid Nanoparticle for Smart Diagnostics of Prostate Cancer.

Prostate cancer is one of the most prevalent cancers afflicting men worldwide, often detected at advanced stages, leading to increased mortality rates. Addressing this challenge, we present an innovative approach employing electrochemical biosensing for early-stage prostate cancer detection. This study used Indium-Tin Oxide (ITO) as a substrate and a deposited gold-graphene quantum dot (Au-GQD) nanohybrid to establish electrochemical sensing platforms for DNA-hybridization assays.

Glycerol-silica/chitosan conjugated self-assembled nano-flower framework for Herstulla thompsoni delivery with effectiveness in natural settings: Optimization and pilot scale production.

Hirsutulla thompsoni (HTS) is an entomopathogenic fungus (EPF), a secure and efficient substitute for synthetic insecticides. However, its susceptibility to degradation in conventional formulations limits its practical use for agricultural practices. In light of current setbacks, this work proposes using a glycerol-silica/chitosan nanoflower gel (NFG) as an efficient delivery system to enhance the efficacy of HTS.