Publications by authors named "K D Peker"

Background: In the socio-dental approach, the integration of normative oral health-related quality of life (OHRQoL) and behavioral propensity measures should be considered when assessing treatment needs and planning oral services. Therefore, this study aimed to evaluate the relationship between oral health impacts attributed to malocclusion and normative and self-perceived orthodontic treatment needs in adolescent patients and to determine the clinical, sociodemographic, and behavioral factors affecting their OHRQoL.

Methods: This cross-sectional study was conducted using a convenience sample size of 105 adolescent patients aged 11-14 years who were referred to the Orthodontics Clinic in the Faculty of Dentistry, Istanbul.

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Purpose: Spinal decompression surgery causes severe pain. Retrolaminar block (RLB) is block, which is done by infiltration of local anesthetic to block spinal nerves between the lamina and superior costotransversospinalis muscle. The primary aim of this study is to evaluate the effectiveness of RLB on postoperative analgesia in patients undergoing spinal surgery.

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Purpose: This study aimed to assess the significance of immunophenotyping and serum cytokines in predicting the clinical progression of acute biliary pancreatitis (ABP).

Materials And Methods: Cytokine levels, T-helper, cytotoxic T, natural killer (NK) cells, monocytes, HLA-DR, and PD-1, as well as PDL-1 immune checkpoints, were measured in ABP patients at the time of diagnosis and compared with results from healthy volunteers. The study also compared leukocyte counts, hematocrit, immunophenotyping results, cytokine statuses, and PD-1, PDL-1 expression between healthy volunteers and ABP subgroups categorized by pancreatitis severity.

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Article Synopsis
  • - A new study synthesized pyrimidine-coupled -β-glucosides and their tetra-acetyl derivatives, focusing on their antimicrobial and anticancer properties compared to existing chemotherapeutics.
  • - The findings indicated strong antiproliferative effects (with activities ranging from 2.29 to 66.84 μg/mL) and significant antibacterial activity against pathogenic bacteria, along with notable cytotoxicity percentages.
  • - Molecular docking studies supported these results, showing that the new compounds bind effectively to CT-DNA, suggesting their potential as promising chemotherapeutic agents deserving further study.
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