The Impact of SARS-CoV-2 on Work Absence: A Cross-Sectional Analysis of Vaccinated and Unvaccinated Workers.

Objectives: Compare SARS-CoV-2 infection and work absence rates between vaccinated and unvaccinated employees during a two-year pandemic period.

Methods: Cross-sectional study with 2,107 participants. Primary outcome: total days missed; main exposure: vaccination status.

Widespread pain phenotypes impact treatment efficacy results in randomized clinical trials for interstitial cystitis/bladder pain syndrome: a Multidisciplinary Approach to the Study of Chronic Pelvic Pain network study.

Pain clinical trials are notoriously complex and often inefficient in demonstrating efficacy, even for known efficacious treatments. A major issue is the difficulty in the a priori identification of specific phenotypes to include in the study population. Recent work has identified the extent of widespread pain as an important determinant of the likelihood of response to therapy, but it has not been tested in clinical trials for the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS).

Nonstationarity in the global terrestrial water cycle and its interlinkages in the Anthropocene.

Climate change and human activities alter the global freshwater cycle, causing nonstationary processes as its distribution shifting over time, yet a comprehensive understanding of these changes remains elusive. Here, we develop a remote sensing-informed terrestrial reanalysis and assess the nonstationarity of and interconnections among global water cycle components from 2003 to 2020. We highlight 20 hotspot regions where terrestrial water storage exhibits strong nonstationarity, impacting 35% of the global population and 45% of the area covered by irrigated agriculture.

Assessing Affective Dimensions of the Interpersonal Circumplex: Development and Validation of the Interpersonal Emotion Inventory.

are feelings distinctively associated with real or imagined interpersonal situations. We propose that interpersonal emotions can be organized within the same circumplex used by contemporary integrative interpersonal theory to organize other aspects of interpersonal functioning. Our research explores the affective dimensions underpinning the interpersonal circumplex (IPC) and maps distinct emotional dispositions using coordinates for agentic and communal affect.