Publications by authors named "K D Lillemoe"
Objective: To investigate the clinicopathological features and long-term outcomes of cystic and solid pancreatic neuroendocrine tumors (PanNETs).
Summary Background Data: PanNETs uncommonly present as cystic lesions. Whether cystic PanNETs represent a distinct clinical entity compared to solid PanNETs is controversial.
Article Synopsis
- Acute pancreatitis is a significant indicator in patients with intraductal papillary mucinous neoplasms (IPMNs), as about 19.2% of patients showed this symptom, often leading to diagnosis.
- Acute pancreatitis is linked to a higher risk of high-grade dysplasia (2.07 times more likely) and certain types of IPMNs, but it is less associated with invasive cancer (0.62 times less likely).
- After surgical resection, 9% of patients with a history of pancreatitis experienced recurrent episodes, compared to only 0.9% in those without prior pancreatitis.
Pancreatic cancer remains a high unmet medical need. Understanding the interactions between stroma and cancer cells in this disease may unveil new opportunities for therapeutic intervention.
View Article and Find Full Text PDFObjective: To describe the design, implementation, and evaluation of a two-week rotation intended to enhance junior surgical residents' preparation for their dedicated professional development time (PDT) and academic careers.
Design: As part of a multifaceted effort to promote residents' academic development, we designed a two-week, nonclinical "Academic Development Block" (ADB) rotation for postgraduate year (PGY)-2 and -3 residents. During this rotation, residents meet with clinical, research, and peer mentors and work on academic activities, with relevant deliverables specific to each class year.
Objective: To describe the long-term natural history of branch duct intraductal papillary mucinous neoplasm (BD-IPMN).
Background: The BD-IPMN is a known precursor of pancreatic cancer, yet its long-term natural history is largely unknown.
Methods: We retrospectively reviewed patients with BD-IPMN who were followed at the Massachusetts General Hospital for at least 10 years without surgical intervention.