Publications by authors named "K D K P Kumari"
Obstructive sleep apnea (OSA), a highly prevalent and serious disorder with significant complications, causes considerable daytime and nighttime symptoms as well as long-term consequences and is yet an underdiagnosed and inadequately treated condition. Patients with OSA undergo frequent awakenings during the sleep cycle and find it impossible to get restorative sleep. Individuals are extremely fatigued, sleepy, and irritable throughout the day.
View Article and Find Full Text PDFTriple-negative breast cancer (TNBC) is a subtype known for its aggressive nature, high rates of recurrence, and treatment resistance, largely attributed to the presence of breast cancer stem cells (BCSCs). Traditional therapies often struggle to eliminate BCSCs, which contributes to tumor recurrence. One promising strategy for addressing this challenge is targeting the Notch signaling pathway, which plays a critical role in the self-renewal and maintenance of BCSCs.
View Article and Find Full Text PDFLaccase is an extracellular enzyme that is widely used in the decolonization of textile dyes in waste water. The aim of our study was to isolate, purify, characterize and immobilize the laccase enzyme produced by HBB 7328. Purified laccase enzyme was immobilized in polyacrylamide gel to explore its ability in decolonization of textile dyes.
View Article and Find Full Text PDFIn cancer patients, physical and psychological issues are very common. There is a need for family support and high utilisation of healthcare resources commonly. Palliative care (PC) has grown in popularity to better fulfil of needs of patients and their families and potentially lowering hospital costs.
View Article and Find Full Text PDFArticle Synopsis
- The study investigated the effectiveness of measuring collapsibility index (CI) of the subclavian vein (SCV) versus the inferior vena cava (IVC) in predicting hypotension after general anesthesia induction in 132 adult patients.
- During quiet breathing, the SCV-CI and IVC-CI had similar sensitivities and specificities, with SCV-CI showing a sensitivity of 68% and IVC-CI showing 70% for predicting postinduction hypotension.
- The findings suggest both measurement methods are moderately accurate, with a significant positive correlation between SCV-CI and IVC-CI, especially during quiet breathing.