Publications by authors named "K D Irwin"

For all vertebrates, the anterior eye structures work together to protect and nourish the eye while ensuring that light entering the eye is correctly focused on the retina. However, the anterior eye structure can vary significantly among different vertebrates, reflecting how the structures of the anterior eye have evolved to meet the specific visual needs of different vertebrate species. Although conserved pathways regulate fundamental aspects of anterior eye development in vertebrates, there may also be species-specific differences underlying structural variation.

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Purpose: The aim of this study was to assess how pandemic-related health concerns and discrimination affected cancer screenings among Asian American women (AAW).

Methods: A two-phase explanatory mixed-methods study was conducted. In phase 1, a survey was distributed among AAW eligible for lung, breast, or colorectal cancer screening to assess delays during the pandemic, concerns about contracting coronavirus disease 2019 (COVID-19), barriers to care, and experiences of discrimination.

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Article Synopsis
  • The study investigates inclusion body myositis (IBM), focusing on the role of TDP-43 protein and its implications in muscle pathology.
  • It found that cryptic peptides linked to TDP-43 were present in 65% of muscle biopsies from IBM patients, but absent in other controls, indicating potential as a biomarker for IBM.
  • The findings suggest that restoring TDP-43 function might help slow down muscle degeneration in patients with this disease.
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The fovea, a pit in the retina, is crucial for high-acuity vision in humans and is found in the eyes of other vertebrates, including certain primates, birds, lizards, and fish. Despite its importance for vision, our understanding of the mechanisms involved in fovea development remains limited. Widely used ocular research models lack a foveated retina, and studies on fovea development are mostly limited to histological and molecular studies in primates.

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Article Synopsis
  • The study investigates effective teaching methods to develop professionalism among healthcare students, highlighting the complexity of professionalism as a skill.
  • A systematic review analyzed 54 articles from healthcare and educational databases, identifying 12 teaching methods, with self-assessment/reflection, group discussion, and lectures being the most prevalent.
  • Results showed that 89% of the studies indicated positive changes in students' professional behaviors or attitudes, providing educators with evidence-based strategies for fostering professionalism in healthcare education.
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