Publications by authors named "K D Hove"
A new biokinetic model for iodine in dairy cows was developed utilizing data from a 4 × 4 factorial feeding experiment with rumen-cannulated cows that were fed rapeseed cake containing substances known to influence iodine metabolism, and soybean meal without such effects. I was administered both intravenously and intra-ruminally to document metabolism pathways. The new model included compartments such as saliva and thyroid gland, often ignored in other models, and in contrast to previously available biokinetic models, it fitted well to our experimental data.
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- CAB + RPV LA is an HIV-1 treatment regimen given every 2 months that was evaluated in the CARISEL study for its effectiveness and patient outcomes after 12 months.
- The study involved 430 patients who switched from daily oral therapy to this long-acting treatment, and the majority maintained low viral loads, with only a small percentage showing signs of treatment failure.
- Overall, CAB + RPV LA was found to be safe, well-tolerated, and effective in keeping patients' HIV levels suppressed.
Implementation of long-acting cabotegravir and rilpivirine: primary results from the perspective of staff study participants in the Cabotegravir And Rilpivirine Implementation Study in European Locations.
J Int AIDS Soc
July 2024
Article Synopsis
- Cabotegravir plus rilpivirine (CAB+RPV) is a long-acting HIV treatment being studied for its implementation effectiveness in European clinics through the CARISEL study.
- The study involved 18 clinics that were divided into two groups: one received standard support, while the other got enhanced support that included more training and team meetings.
- Staff participants (SSPs) reported high acceptability, appropriateness, and feasibility scores for CAB+RPV throughout the year, indicating positive feedback on its implementation, with no significant differences noted between the two support groups.
Background: Simulated cases are widely used in medical education to develop clinical reasoning skills and discuss key topics around patient care. Such cases present an opportunity to demonstrate real world encounters with diverse patient and health provider identities, impacts of social and structural determinants of health, and demonstrate a generalist approach to problems. However, despite many calls-to-action for medical schools to better incorporate equity, diversity and inclusion (EDI) and generalism, it remains difficult to evaluate how well these goals are being met.
View Article and Find Full Text PDFBackground: The treatment of borderline resectable (BR) and locally advanced (LA) pancreatic ductal adenocarcinoma (PDAC) has evolved with a wider application of neoadjuvant chemotherapy (NACHT). The aim of this study was to identify predictive factors for survival in BR and LA PDAC.
Methods: Clinicopathologic data of patients with BR and LA PDAC who underwent surgical exploration between January 2011 and June 2021 were retrospectively collected.