Publications by authors named "K Cierkens"

This paper illustrates how a dynamic model can be used to evaluate a plant upgrade on the basis of post-upgrade performance data. The case study is that of the Eindhoven wastewater treatment plant upgrade completed in 2006. As a first step, the design process based on a static model was thoroughly analyzed and the choices regarding variability and uncertainty (i.

View Article and Find Full Text PDF

A shift from batch processing towards continuous processing is of interest in the pharmaceutical industry. However, this transition requires detailed knowledge and process understanding of all consecutive unit operations in a continuous manufacturing line to design adequate control strategies. This can be facilitated by developing mechanistic models of the multi-phase systems in the process.

View Article and Find Full Text PDF

Application of activated sludge models (ASMs) to full-scale wastewater treatment plants (WWTPs) is still hampered by the problem of model calibration of these over-parameterised models. This either requires expert knowledge or global methods that explore a large parameter space. However, a better balance in structure between the submodels (ASM, hydraulic, aeration, etc.

View Article and Find Full Text PDF
Legal aspects of E-HEALTH.

Stud Health Technol Inform

December 2008

Cross-border activities in health care in the European single market are increasing. Many of these cross-border developments are related to e-Health. E-Health describes the application of information and communication technologies across the whole range of functions that affect the health care sector.

View Article and Find Full Text PDF