Comparison of temperature resolution of single-band, dual-band, and multiband infrared systems.

A new measure of temperature resolution of IR systems called noise-generated error (NGE) was recently proposed. The NGE does not have limitations of the classical noise-equivalent temperature difference and can be used to describe the resolution of single-band, dual-band, and multiband IR measurement systems. The results of theoretical and experimental testing of the temperature resolution NGE of a developed model of single-band, dual-band, and multiband pyrometers are presented.

Errors of temperature measurement with multiband infrared systems.

A model of the errors of temperature measurement with multiband systems was developed. Calculations of these errors for some measurement conditions and systems were carried out. It was shown that multiband systems are capable of producing accurate results of noncontact temperature measurement only in a limited number of applications and that to have small internal errors, they must be designed and built with much greater care than in the case of typical single-band systems.

Measure of the influence of detector noise on temperature-measurement accuracy for multiband infrared systems.

The noise-equivalent temperature difference is a measure of the detector-noise-limited sensitivity of single-band IR systems for noncontact temperature measurement. However, because its definition is based on the signal-to-noise ratio in a single detector channel, the notion of noise-equivalent temperature difference must be generalized in case of dual-band or multiband IR systems. A new measure of temperature-measurement sensitivity is proposed that can be used to describe single-band, dual-band, and multiband IR measurement systems.

Acetylsalicylic acid as a potential regulator of prolidase-convertible pro-drugs in control and neoplastic cells.

Proline analogue of melphalan (Mel-pro) is one of the pro-drugs activated by prolidase, cytoplasmic imidodipeptidase highly expressed in some neoplastic tissues. In order to limit the action of prolidase on the pro-drug in normal cells, prolidase inhibitor, acetylsalicylic acid (ASA), was tested in fibroblasts (showing average prolidase activity for normal cells) and in MDA-MB 231 breast cancer cells (showing elevated activity of the enzyme). The effect of Mel-pro in the presence and absence of ASA on prolidase activity (colorimetric assay), DNA biosynthesis (3H-thymidine incorporation assay), cytotoxicity (tetrazoline assay) and ability to penetrate cell membrane (thin layer chromatography) in both type of cells was measured.

Proline analogue of melphalan as a prodrug susceptible to the action of prolidase in breast cancer MDA-MB 231 cells.

Proline analogue of melphalan (Mel-pro) was synthesized as a prodrug susceptible to the action of ubiquitously distributed, cytosolic imidodipeptidase-prolidase [E.C.3.