Publications by authors named "K Chopra"
Objectives: To determine the prevalence of psychiatric morbidities in survivors of pediatric acute lymphoblastic leukemia (ALL) and to identify any risk factors.
Methods: Survivors of ALL, who had completed their treatment, atleast two or more years ago and now were 6-18 y old were enrolled on the study. The Mini International Neuropsychiatric Interview (M.
Nucleic acids (RNA and DNA) play crucial roles in all living organisms and find wide utility in clinical settings. The convergence of rationally designed nucleic acid multistranded assemblies with embedded therapeutic properties has led to the development of a platform based on nucleic acid nanoparticles (NANPs). NANPs incorporate various functional moieties to deliver their combinations to diseased cells in a highly controlled manner.
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- This text discusses the effectiveness and risks of revising failed shoulder surgeries using total shoulder arthroplasty (TSA), especially in comparison to reverse prostheses which have been more successful in revisions.
- A systematic review analyzed 13 studies with 312 patients, finding that 39% had complications and 12% needed further revision. Several clinical outcomes improved post-surgery, but they weren't statistically significant.
- The study concludes that while revision to TSA can be suitable for some patients, the high complication rates and specific challenges like glenoid loosening limit its overall viability as a revision option.
Article Synopsis
- Variations in access to drugs globally make it hard to assess the effectiveness of modern treatments for patients with relapsed and refractory mature T-cell and NK-cell lymphomas in a study of 925 patients.
- * The study found that relapsed lymphoma patients had better overall survival rates compared to refractory patients after second-line treatment, with several factors identified as predictors of survival.
- * A new prognostic index (PIRT) categorizes patients based on risk factors into low, intermediate, or high risk, impacting 3-year overall survival rates, and highlights the superior outcomes of novel therapies compared to traditional chemotherapy.
Article Synopsis
- The study investigates the prevalence of anxiety and depression among homeless individuals diagnosed with Pulmonary Tuberculosis (PTB) in Delhi, highlighting the serious relationship between homelessness, mental health, and infectious diseases.
- Out of 47 PTB patients screened, a staggering 95.7% exhibited symptoms of depression, while varying levels of anxiety were also identified, indicating significant mental health issues within this population.
- The findings suggest that many patients were unaware of their PTB status, emphasizing the urgent need for mental health assessments among homeless PTB patients in India to address the growing burden of mental illnesses in this overlooked group.