Publications by authors named "K Chojnowski"
Article Synopsis
- - Lesch-Nyhan Disease (LND) is a rare genetic disorder caused by mutations in a specific gene, resulting in neurological issues like abnormal movement and self-harm, which are hard to treat.
- - A systematic review of 34 studies found that many had high bias, and there were significant differences in how treatments were applied and evaluated, leading to inconsistent results.
- - The most researched treatments, such as S-Adenosylmethionine and Deep Brain Stimulation, need more investigation, and there is a pressing need for better study designs to improve the assessment of treatment effectiveness in LND.
Stroke is a life-threatening condition in which accurate diagnoses and timely treatment are critical for successful neurological recovery. The current acute treatment strategies, particularly non-invasive interventions, are limited, thus urging the need for novel therapeutical targets. Arginine vasopressin (AVP) receptor antagonists are emerging as potential targets to treat edema formation and subsequent elevation in intracranial pressure, both significant causes of mortality in acute stroke.
View Article and Find Full Text PDFIntroduction: Patient adherence to a prophylactic regimen is important for optimal benefit of hemophilia treatment. Despite a growing number of adults with hemophilia in Poland receiving secondary prophylaxis, data on adherence to the regimen are limited.
Objectives: The aim of the study was to assess adherence to secondary prophylaxis in Polish adults with severe hemophilia.
Kienböck's disease is a rare disease described as progressive avascular osteonecrosis of the lunate. The typical manifestations include a unilateral reduction in wrist motion with accompanying pain and swelling. Besides recent advances in treatment options, the etiology and pathophysiology of the disease remain poorly understood.
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