Multidisciplinary advisory teams to manage multidrug-resistant tuberculosis: the example of the French Consilium.

The World Health Organization (WHO) recommends that multidrug-resistant tuberculosis (MDR-TB) treatment should be managed in collaboration with multidisciplinary advisory committees (consilia). A formal national Consilium has been established in France since 2005 to provide a centralised advisory service for clinicians managing MDR-TB and extensively drug-resistant (XDR-TB) cases. Review the activity of the French TB Consilium since its establishment.

[The prevention of tuberculosis through screening].

Tuberculosis is one the world's biggest health problems. The prevention of this disease is adapted to the epidemiological situation and the economic constraints of each country. The correct treatment of patients as well as the care of people having been in contact with them are very effective methods which lead to the drop in the incidence and morbidity of tuberculosis.

[Neonatal exposure to active pulmonary tuberculosis in a maternity ward: screening and clinical course of a cohort of exposed infants].

Unlabelled: Few data are available on the impact of a tuberculosis exposure on newborns in a maternity ward.

Objectives: To describe the screening and clinical course of infants exposed during the neonatal period to a caregiver with bacillary tuberculosis.

Patients And Methods: Infants exposed during the postnatal period in a maternity unit in Paris, from March to August 2005, to a caregiver with bacillary tuberculosis were included in a standardized screening protocol.

Glucocorticoids reduce inflammation in cystic fibrosis bronchial epithelial cells.

Reduction of lung inflammation is one of the goals of cystic fibrosis (CF) therapy. Among anti-inflammatory molecules, glucocorticoids (GC) are one of the most prescribed. However, CF patients seem to be resistant to glucocorticoid treatment.

Management of young children in contact with an adult with drug-resistant tuberculosis, France, 2004-2008.

Setting: Drug-resistant tuberculosis (DR-TB) is increasing worldwide and may be a source of diagnostic and therapeutic problems in young exposed children. In France exposed children are systematically treated with 3-month isoniazid-rifampicin prophylaxis.

Objective: To describe the characteristics and management of children aged <2 years in contact with an adult case of DR-TB in France over a 5-year period (2004-2008).