Publications by authors named "K Chabita Saha"
Intussusception in adults is a rare condition, often associated with an underlying pathological lead point. This case report describes a case of intussusception in a 37-year-old female patient with an unusual lead point: an appendicular mucinous neoplasm. This case highlights the clinical presentation, diagnostic process, and management of adult intussusception caused by an appendicular neoplasm.
View Article and Find Full Text PDFObjective: This study's objective is to analyze the prevalence as well as the configuration of second mesiobuccal (MB2) in maxillary 2 molars and predict its existence based on mesiobuccal-palatal (MB-P) distance, MB-P/distobuccal-palatal (DB-P) distance ratio and mesiobuccal, distobuccal, and palatal orifice (MDP) angle with the help of cone-beam computed tomography.
Materials And Methods: The presence and absence of MB2 are noted down in 300 maxillary 2 molars. Canal configuration was observed from the orifice to the apex in the mesiobuccal root.
Tight junction regulation, intestinal permeability, and mucosal immunity in gastrointestinal health and disease.
Curr Opin Gastroenterol
January 2025
Purpose Of Review: The contributions of intestinal barrier loss, that is, increased permeability, to multiple disorders, including inflammatory bowel disease (IBD), have been a topic of speculation for many years, and the literature is replete with conclusions based on correlation and speculation. The goal of this article is to critically review recent advances in mechanistic understanding of barrier regulation and the evidence for and against contributions of intestinal barrier loss to disease pathogenesis.
Recent Findings: It is now recognized that intestinal permeability reflects the combined effects of two distinct routes across tight junctions, which form selectively permeable seals between adjacent epithelial cells, and mucosal damage that leads to nonselective barrier loss.
Article Synopsis
- Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive tumor that develops from plasmacytoid dendritic cell precursors and usually affects the skin and bone marrow.
- A case study of a 30-year-old male patient highlights skin lesions filled with undifferentiated blast-like cells, identifiable by specific markers but not by B-cell or T-cell indicators.
- Timely diagnosis and a multidisciplinary treatment approach are critical to prevent the disease's progression and improve patient outcomes, as misdiagnosis can lead to severe complications.