Redo Tricuspid and Pulmonary Valve Replacement with On-X in Renal Transplant Patient: A Case Report.

Surgical treatment is recommended in patients with symptomatic severe tricuspid regurgitation and pulmonary regurgitation. Although renal transplant patients are a high-risk patient group for cardiac surgery, heart valve surgeries can be performed successfully. There are a limited number of studies published on this subject in the literature.

Retinal and choroidal microvascular changes during pregnancy detected with OCTA.

Objective: To investigate choroidal and retinal blood flow and thickness changes using optical coherence tomography and optical coherence tomography angiography during pregnancy.

Design: Prospective and case-control study between June 2020 and June 2021.

Methods: This prospective study included 41 eyes of 41 pregnant females and 45 eyes of 45 healthy nonpregnant females.

A High-Content Screen Identifies TPP1 and Aurora B as Regulators of Axonal Mitochondrial Transport.

Dysregulated axonal trafficking of mitochondria is linked to neurodegenerative disorders. We report a high-content screen for small-molecule regulators of the axonal transport of mitochondria. Six compounds enhanced mitochondrial transport in the sub-micromolar range, acting via three cellular targets: F-actin, Tripeptidyl peptidase 1 (TPP1), or Aurora Kinase B (AurKB).

Facilitators of and barriers to high-resolution anoscopy adherence among men who have sex with men: a qualitative study.

Unlabelled: Background Anal cancer is a rare malignancy that disproportionately affects men who have sex with men (MSM) and HIV-infected people. Anal cancer is associated with human papillomavirus (HPV) in upward of 90% of cases and is preceded by pre-cancerous changes in cells of the anal canal. High-resolution anoscopy (HRA) is used for the detection, treatment and continued monitoring of anal dysplasia.