Publications by authors named "K Cederlund"
Article Synopsis
- - The study investigates the prevalence of chronic airflow limitation (CAL), emphysema, and impaired lung diffusing capacity (Dl) in a middle-aged Swedish population (ages 50-64) in relation to smoking habits and respiratory symptoms.
- - Results showed that 8.8% had CAL and emphysema, and 5.7% had impaired Dl, with higher rates in current smokers compared to ex-smokers and never-smokers.
- - The research indicates that CAL and impaired Dl are linked to common respiratory symptoms, while asthma in never-smokers with CAL shows distinct characteristics that may require different clinical management than traditional smoking-related COPD.
Reduced lung function is associated with cardiovascular mortality, but the relationships with atherosclerosis are unclear. The population-based Swedish CArdioPulmonary BioImage study measured lung function, emphysema, coronary CT angiography, coronary calcium, carotid plaques and ankle-brachial index in 29,593 men and women aged 50-64 years. The results were confirmed using 2-sample Mendelian randomization.
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- - The study aimed to assess the prevalence of atherosclerosis in coronary and carotid arteries among individuals with prediabetes and diabetes compared to those without diabetes, involving over 30,000 participants aged 50-64.
- - The findings revealed that participants with prediabetes or diabetes had significantly higher levels of coronary artery plaque, stenosis, and calcium scores compared to normoglycaemic individuals, indicating a greater cardiovascular risk.
- - Notably, the prevalence of coronary atherosclerosis was highest in those with known diabetes, while both prediabetic and diabetic participants showed increased plaque in carotid arteries compared to normoglycaemic individuals.
Article Synopsis
- Interstitial lung abnormalities (ILA) are often found accidentally in chest CT scans and can indicate early signs of fibrotic lung disease, prompting a study on their prevalence in Sweden, especially among never-smokers.
- A total of 29,521 participants aged 50-64 were analyzed, revealing that 9.7% had ILA, with lower prevalence in never-smokers at 7.9%, and both groups showing little to no difference in reported symptoms.
- The study suggests that ILA are common in this demographic, raising concerns that never-smokers might be overlooked in screenings and therefore underdiagnosed.