Publications by authors named "K Catt"
Article Synopsis
- The Concise Guide to PHARMACOLOGY 2023/24 offers a summarized overview of approximately 1800 drug targets and around 6000 interactions with 3900 ligands, mostly in a tabular format.
- It focuses on selective pharmacology and includes links to an open access knowledgebase for more detailed drug information.
- The guide divides drug targets into six major categories, providing essential summaries and guidance based on the latest pharmacological data available as of mid-2023, while serving as an official resource by the International Union of Basic and Clinical Pharmacology.
Angiotensin II (Ang II) is a critical regulator of insulin signaling in the cardiovascular system and metabolic tissues. However, in adipose cells, the regulatory role of Ang II on insulin actions remains to be elucidated. The effect of Ang II on insulin-induced insulin receptor (IR) phosphorylation, Akt activation, and glucose uptake was examined in 3T3-L1 adipocytes.
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- The Concise Guide to Pharmacology 2021/22 offers a streamlined overview of nearly 1900 human drug targets, focusing on selective pharmacology and organized mainly in tables for quick reference.
- The guide serves as a reliable, citable resource that distills extensive online content while ensuring it reflects the status as of mid-2021, distinct from ongoing database updates.
- Key pharmacological targets include G protein-coupled receptors, ion channels, and enzymes, with official nomenclature and references provided to assist further research and understanding.
In the present study, we determined the cellular regulators of ERK1/2 and Akt signaling pathways in response to human CRF receptor (CRFR) activation in transfected COS-7 cells. We found that Pertussis Toxin (PTX) treatment or sequestering Gβγ reduced CRFR-mediated activation of ERK1/2, suggesting the involvement of a G-linked cascade. Neither G/PKA nor G/PKC were associated with ERK1/2 activation.
View Article and Find Full Text PDFCorrection for 'Aptamer-functionalized neural recording electrodes for the direct measurement of cocaine in vivo' by I. Mitch Taylor et al., J.
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