Recent advances in computational methods have led to considerable progress in the design of self-assembling protein nanoparticles. However, nearly all nanoparticles designed to date exhibit strict point group symmetry, with each subunit occupying an identical, symmetrically related environment. This limits the structural diversity that can be achieved and precludes anisotropic functionalization.
View Article and Find Full Text PDFAtraumatic wrist pain can be due to a variety of causes including gout, pseudogout, cellulitis, arthritis flare, or infection of the joint. One important differential to rule out immediately is septic arthritis as it is considered an orthopedic emergency. Due to the rarity of septic arthritis in the wrist, there is limited data to guide diagnosis and treatment.
View Article and Find Full Text PDFTo evaluate the accuracy and consistency of chatbots in answering questions related to special needs dentistry. Nine publicly accessible chatbots, including Google Bard, ChatGPT 4, ChatGPT 3.5, Llama, Sage, Claude 2 100k, Claude-instant, Claude-instant-100k, and Google PaLM, were evaluated on their ability to answer a set of 25 true/false questions related to special needs dentistry and 15 questions for syndrome diagnosis based on their oral manifestations.
View Article and Find Full Text PDFBackground: Few studies of migraine have evaluated migraine disability across multiple countries using the same methodology.
Methods: This cross-sectional, web-based survey was conducted in 2021-2022 in Canada, France, Germany, Japan, UK and USA. Respondents with migraine were identified based on modified International Classification of Headache Disorders, 3rd edition, criteria.