Publications by authors named "K C N Rabelo"
Article Synopsis
- Obesity is a chronic disease associated with health risks like nonalcoholic fatty liver disease (NAFLD), and capybara oil (CO) shows potential as a treatment.
- The study involved C57Bl/6 mice on a high-fat diet, examining the effects of CO on various health parameters over 18 weeks.
- While CO didn't significantly change physiological parameters, it improved liver cell structure and reduced steatosis and apoptosis, indicating its promise in NAFLD treatment.
Dengue virus (DENV) and chikungunya (CHIKV) are arthropod-borne viruses belonging to the and families, respectively. Infection by both viruses can lead to a mild indistinct fever or even lead to more severe forms of the diseases, which are characterized by a generalized inflammatory state and multiorgan involvement. Infected mothers are considered a high-risk group due to their immunosuppressed state and the possibility of vertical transmission.
View Article and Find Full Text PDFPurpose: To evaluate the improvement of selected mechanical properties of a resin-modified glass-ionomer cement (RMGIC) with a discontinuous short E glass fiber flowable resin composites (GFRRC) to be used in load-bearing areas of permanent teeth.
Methods: Experimental materials were prepared using two different weight proportions, 7 wt% (1.75% E glass fibers) and 25 wt% (6.
Liver immunopathogenesis in fatal cases of dengue in children: detection of viral antigen, cytokine profile and inflammatory mediators.
Front Immunol
July 2023
Article Synopsis
- Dengue virus (DENV) is a major global health issue, particularly affecting tropical regions, and can cause severe illness in some patients, though the reasons behind this severity are not completely understood.
- This study aimed to analyze liver tissues from three children who died from DENV to identify histopathological features, cytokine profiles, and immune cell populations.
- Findings revealed significant liver damage, including vascular dysfunction and increased inflammatory cells, suggesting that these factors contribute to severe liver complications in children infected with DENV.
Obesity is an inflammatory disease associated with secondary diseases such as kidney disease, which can cause lipotoxicity, inflammation and loss of organ function. Polyunsaturated fatty acids act in the production of lipid mediators and have anti-inflammatory characteristics. In this work, the objective was to evaluate renal histopathology in obese mice and the effects of treatment with capybara oil (CO) (5000 mg/kg/day for 4 weeks).
View Article and Find Full Text PDF