Background: Labor induction is a common obstetric intervention, increasingly performed worldwide, often using prostaglandins like misoprostol and dinoprostone.
Objective: This study aims to compare the effectiveness and safety of intravaginal misoprostol versus dinoprostone for inducing labor, examining their impact on various maternal and neonatal outcomes.
Methods: A systematic review and meta-analysis were conducted using four databases-PubMed, Google Scholar, EBSCO, and the Cochrane Library-from January 2000 to April 2023.
Unlabelled: is the most common, globally detected nosocomial fungal pathogen with multi-drug resistance. The high prevalence of infections has raised concern about drug resistance and adverse effects, compounded by a lack of effective alternative drugs. Bioengineered nanomaterials play a significant role in combating nosocomial infections.
View Article and Find Full Text PDFIn order to explore the ways knowledge travels across spatial and cultural boundaries, this article focuses on the intriguing case of the Edinburgh-trained Scottish surgeon James Esdaile (1808-59), who, after practising conventional surgery for almost fifteen years in British colonial India, quite unexpectedly turned to mesmeric anaesthesia in the last five years of his service. By following his career and his mesmeric turn, the article describes Esdaile's subsequent public experiments in mesmeric anaesthesia in collaboration with indigenous practices and practitioners of trance induction in the 1840s which led to the creation of a special mesmeric hospital in Calcutta. Although very successful, it eventually ceased to function, apparently victim to new and cheaper chemical anaesthetics.
View Article and Find Full Text PDFMeningitis retention syndrome (MRS) represents a rare condition in which there is meningitis accompanied by urinary retention in the absence of any other neurological symptoms. MRS is usually misdiagnosed as a urinary tract infection due to varied clinical symptoms. It is a self-limiting syndrome that often presents with prodromal symptoms of meningitis.
View Article and Find Full Text PDFObjectives: Deauville scores (DS) from PET/CT imaging are increasingly being used to direct response-adjusted treatment strategies in lymphoma, including large B cell lymphomas (LBCL). We aimed to investigate the outcome of allogeneic haematopoietic stem cell transplantation (alloHSCT) in LBCL and the role played by pre-transplant disease status, as determined by DS.
Methods: We performed a retrospective, observational study of adults treated with a T-cell depleted alloHSCT for de novo DLBCL or high-grade transformation.