Effects of the Water Resistance Therapy Program on Behavioral Dysphonia: A Physiological Therapeutic Proposal Based on the Principles of Sensorimotor Learning.

Introduction: The main goal of voice therapy is to reestablish the balance of the vocal system through myoelastic and aerodynamic forces. Therefore, the therapeutic method must focus on vocal physiology as a way of reversing the pathology and also be easy for the patient to internalize it. Water resistance therapy (WRT) can meet this demand.

1,25(OH)2D3 increase osteogenic potential of human periodontal ligament cells with low osteoblast potential.

Objective: Periodontal dental ligament mesenchymal stem cells (PDLMSCs) play a major role in periodontal tissue regeneration by the neoformation of root cementum and alveolar bone. These cells are highly heterogeneous, and many present low potential to renovate the hard tissue damaged by periodontal disease. A previous study found that the low osteoblast/cementoblast (O/C) differentiation potential of PDLMSCs is related to high asporin (ASPN) expression, which was identified as a negative regulator of PDL cells differentiation and mineralization, suppressing BMP-2-induced O/C differentiation.

CCKR signaling map, G-Protein bindings, hormonal regulation, and neural mechanisms may influence the osteogenic/cementogenic differentiation potential of hPDLSCs.

Objective: Periodontal regeneration poses challenges due to the periodontium's complexity, relying on mesenchymal cells from the periodontal ligament (hPDLSCs) to regenerate hard tissues like bone and cementum. While some hPDLSCs have high regeneration potential (HOP-hPDLSCs), most are low potential (LOP-hPDLSCs). This study analyzed hPDLSCs from a single donor to minimize inter-individual variability and focus on key differences in differentiation potentials.

Water Resistance Therapy in Individuals with Parkinson's Disease: A Session-by-Session Analysis of the Vocal Quality.

Objectives: Verify session-by-session effects of the water resistance therapy (WRT) on the vocal quality of individuals with Parkinson's disease (PD).

Methods: This is a retrospective analytical study. Then, the samples were acquired from a database composed of 10 men aged between 50 and 90 years old diagnosed with PD.

Perceptual-Auditory and Acoustic Analysis of Breathiness in Cis and Transgender Men and Women.

Objective: To verify breathiness in the cisgender and transgender men and women's voices, compare values of acoustic and perceptual indicators of breathiness and fundamental frequency (f0) between groups, and compare them between the voices attributed as female and male.

Study Design: Cross sectional retrospective study.

Methods: The study was approved by the Research Ethics Committee (4,937,140).