Publications by authors named "K Buvanesvaragurunathan"
Hepatoprotective Constituents of Macrocybe gigantea (Agaricomycetes) from India.
Int J Med Mushrooms
November 2022
Non-alcoholic fatty liver disease (NAFLD) is one of the most frequent, chronic liver diseases worldwide and currently has no specific therapy. Our previous study indicated the anti-NAFLD effect of Macrocybe gigantea (Massee) Pegler & Lodge in high-fat diet-fed animals. This study aimed to isolate and identify the active hepatoprotective constituents from M.
View Article and Find Full Text PDFGlycyrrhetinic acid (GA) is one of the important Pentacyclic Triterpenoids (PT) found in the roots of licorice. This study aimed to evaluate the in vitro growth inhibitory effect of 18β-GA (18β-Glycyrrhetinic acid) and C-30 esters against Theileria annulata, the causative agent of Tropical Bovine Theileriosis. C-30 esters of 18β-GA were synthesized and their structures were elucidated using spectroscopy.
View Article and Find Full Text PDFNon-alcoholic Fatty Liver Disease (NAFLD) is one of the growing epidemics of the globe. This study was aimed to evaluate the anti-NAFLD effect of selected IAN derivatives using in silico, in vitro and in vivo models. In silico tools viz.
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- Increasing global interest in herbal health supplements for obesity is noted, with a focus on Spermacoce hispida L. seeds, traditionally used for obesity treatment in Tiruvallur district, Tamil Nadu, India.
- The study aimed to validate this traditional use and identify the active component with antihyperlipidemic properties through bioassay-guided fractionation, leading to the discovery of deacetylasperulosidic acid (DAA).
- DAA demonstrated significant antihyperlipidemic effects in experimental models, reducing lipid levels and adipocyte proliferation, thereby supporting its potential as a treatment for obesity and related conditions.
The prevalence of Non Alcoholic Fatty Liver Disease (NAFLD) is increasing globally. Terminalia arjuna W. & Arn.
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