Publications by authors named "K Bulsara"
Background: Dorsal thoracic arachnoid web is a rare diagnosis and is not commonly seen in neurosurgical practice. Patients can present with symptoms and signs of thoracic myelopathy in the setting of an arachnoid cyst and a presyrinx state.
Observations: A 57-year-old male with a 10-year history of worsening bilateral leg weakness and chronic back pain re-presented to the neurosurgery clinic after being seen by neurology and orthopedic spine surgery.
Article Synopsis
- * The study analyzes RNA sequencing data from 486 meningioma samples across three DNA methylation groups, discovering key splicing alterations that correlate with tumor recurrence and patient outcomes, while also identifying important splicing factors like SRSF1 in Hypermitotic meningiomas.
- * The findings emphasize RNA splicing as a crucial aspect of meningioma characteristics, presenting opportunities for prognostic tools and novel RNA-based therapies targeting identified splicing changes.
This article reviews the major devices, individuals, and other historical landmarks in the development of suction in the field of neurosurgery, where the operating fields are characteristically deep and narrow. Our review spans the 159 years since the first use of aspiration in surgery to modern applications. This report exemplifies a comprehensive history of suction, the minute iteration of devices, and the massive impact this technological development has had on medicine and neurosurgery.
View Article and Find Full Text PDFHeparin-induced thrombocytopenia is a rare and potentially devastating complication of heparin therapy. Patients with an absolute indication for anticoagulation, such as those with significant pulmonary embolism, must be switched to a different anticoagulant, such as argatroban, a direct thrombin inhibitor. We report a case of anaphylaxis to argatroban in a patient who was initially on heparin for intermediate-high risk pulmonary embolism but developed suspected type II heparin-induced thrombocytopenia.
View Article and Find Full Text PDFArticle Synopsis
- * Dizziness can be categorized into subtypes like vertigo, disequilibrium, presyncope, or lightheadedness, leading to a focus on timing and triggers for diagnosis rather than just symptom types.
- * The document provides guidance for selecting appropriate diagnostic imaging based on established clinical frameworks and evidence-based guidelines from expert panels, utilizing methods like GRADE to evaluate the available research.