Monitoring the Spread of Multidrug-Resistant Throughout the Broiler Production Cycle.

The extensive use of antimicrobials in broiler production is changing the bird microbiota, fostering drug-resistant bacteria, and complicating therapeutic interventions, making the problem of multidrug resistance global. The monitoring of antimicrobial virulence and resistance genes are tools that have come to assist the breeding of these animals, directing possible treatments as already used in human medicine and collecting data to demonstrate possible dissemination of multidrug-resistant strains that may cause damage to industry and public health. This work aimed to monitor broiler farms in southern Brazil, isolating samples of and classifying them according to the profile of resistance to antimicrobials of interest to human and animal health.

Role of mesenchymal stromal cell secretome on recovery from cellular senescence: an overview.

Cellular senescence is intricately linked with numerous changes observed in the aging process, including the depletion of the stem cell pool and the decline in tissue and organ functions. Over the past three decades, efforts to halt and reverse aging have intensified, bringing rejuvenation closer to reality. Current strategies involve treatments using stem cells or their derivatives, such as the secretome.

Unveiling the unknown diversity of planktonic green algae (Chlorophyta) in urban ponds in the semiarid region of Northeastern Brazil.

This study examined the taxonomic composition and ecological aspects of planktonic green algae (Chlorophyta) in four urban ponds (Parque da Lagoa, Lagoa Grande, Laguneville, and Pindoba) in Feira de Santana, Bahia State, Brazil. We analyzed 96 samples collected bimonthly in 2022 and identified 54 taxa, with the majority (42) classified as uncommon or sporadic. The most common species were Monoraphidium circinale and Lemmermannia komarekii, found in 100% and 95.

Predicting adjuvant radiation therapy benefit in cutaneous squamous cell carcinoma with the 40-gene expression profile.

To independently confirm that the 40-gene expression profile (40-GEP) test can identify patients with high-risk cutaneous squamous cell carcinoma who are more or less likely to benefit from adjuvant radiation therapy (ART). Primary cutaneous squamous cell carcinoma tumors from two academic centers received retrospective 40-GEP testing and were analyzed for 5-year metastasis-free survival and projected time to event. Random sampling of matched patient pairs ( = 52 ART-treated; 371 no ART) showed a median 50% decrease in 5-year progression rate for ART-treated patients (vs no ART) with 40-GEP Class 2B.