Publications by authors named "K Brennan Sara"

Orbital involvement in Sinonasal tumours most commonly present as proptosis, epiphora and/or visual symptoms. We aimed to enumerate the orbital manifestations of Sino nasal tumours, to describe strategies employed to manage orbit and vision, to evaluate outcomes, vision preservation and survival rates. This retrospective study spanning ten years identified 147 Sino nasal pathologies with clinic-radiological involvement of the orbit.

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Article Synopsis
  • The study evaluates the use of apparent diffusion coefficient (ADC) values in MRI to differentiate between fungal and bacterial skull base osteomyelitis (SBO).
  • Researchers conducted a retrospective review of 142 SBO patients and found that the most common pathogens were Pseudomonas, Aspergillus, and Staphylococcus aureus.
  • Despite noting a difference in the average ADC values between infected and normal tissues, the results showed no significant difference between the ADC values of bacterial and fungal SBO, highlighting the importance of early biopsies for accurate diagnosis.
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Diabetes muscle infarction (DMI) is a rare complication of diabetes in which patients who present with DMI more commonly have some form of kidney disease in addition to diabetes mellitus. DMI typically presents with muscle pain and swelling. Diagnosis typically requires imaging (MRI with gadolinium contrast is the gold standard) and a variety of laboratory studies may aid in the diagnosis.

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A man in his 20s came for maxillofacial consultation with a pus discharge from the left preauricular region for the last 1 year. He had met with a road traffic accident 2 years earlier and had received surgical treatment for injuries associated with the same. Investigations revealed multiple impacted foreign bodies deep within his facial structures.

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Sino nasal carcinogenesis is attributed to numerous factors, namely tobacco, alcohol and snuff as the most common. Human Papilloma virus (HPV) has been associated with aetiopathogenesis of malignancies in the upper aerodigestive tract (UADT). The prevalence of HPV in Sino-nasal malignancy (SNM) which is closely related to UADT in location is not known.

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