Publications by authors named "K Bray"
Background: Biopsychosocial changes during adolescence are thought to confer risk for emotion dysregulation, and in particular, anxiety disorders. However, there are substantial gaps in our knowledge about the biological mechanisms underlying anxiety during adolescence, and whether this contributes to the higher prevalence in females. The Puberty and NeuroDevelopment in Adolescents (PANDA) study aims to examine links between biological (sex hormones, cortisol) and social environmental factors and brain function during adolescence, with a focus on key processes (emotion regulation, fear learning) identified as relevant for the development of anxiety disorders.
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- Therapeutic drug monitoring (TDM) for anti-tumor necrosis factor (anti-TNF) treatments in inflammatory bowel disease (IBD) can improve treatment outcomes and manage failures more cost-effectively, but slow lab results hinder its widespread use.
- *To address this issue, point-of-care technology tests (POCTs) offer rapid results at the patient's location, allowing for faster treatment decisions compared to the current standard method, the ELISA assay.
- *This study evaluated a new POCT method (ProciseDx) against the standard ELISA method for measuring drug levels in IBD patients and found a strong correlation between the two, suggesting the POCT could be a practical alternative in clinical settings.*
Background/objectives: Although there is a need for evidence-based physical activity programs in rural communities, evaluating such programs is often challenging due to access-related barriers and measurement tools that are not designed for rural contexts. This study aimed to explore and better understand the day-to-day experiences of rural-dwelling children using wrist-worn PA trackers as part of a study to develop a health promotion program.
Methods: Ten caregivers and child dyads were enrolled ( = 20).
Background: Transcutaneous electrical nerve stimulation (TENS) is a non-invasive modality that utilizes electrical currents to modulate pain in populations with acute and chronic pain. TENS has been demonstrated to produce hypoalgesic effects in postoperative pain, fibromyalgia, knee osteoarthritis, and healthy subjects. Transcutaneous auricular vagus nerve stimulation (TaVNS) is a non-invasive modality that modulates the vagus nerve by stimulating its auricular branches.
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- The study aimed to understand different recovery patterns in neurocognitive function after pediatric concussions over three months and identify factors that influence recovery trajectories.
- Researchers analyzed data from 74 kids aged 8-17 and found three distinct recovery groups: two groups showed improvement in information processing, while one group had minimal change and lower scores on cognitive tests.
- The findings highlighted that a previous history of headaches was linked to the group with the least improvement, suggesting that pre-existing conditions could help identify children who may need more support after a concussion.