Religious Characteristics of Nurses Who Refer Patients to Chaplains at a Catholic Hospital in the Northwestern USA.

The purpose of this study was to assess the association between nurse religiosity and decision to consult spiritual care services at a hospital in the western USA. An anonymous survey was distributed to assess nurses' reports of whether they would request spiritual care services across different scenarios. Out of 171 nurses approached to participate in this survey, fifty-one nurses completed the survey and half of respondents considered themselves religious.

Nursing and Chaplain Partnership for Pain Management: A Survey of Nurses.

Purpose: Pain is a universal experience for hospitalized patients, with physical, psychological, spiritual, and cognitive implications. As hospitals seek to identify nonpharmaceutical options for managing acute pain, the role of chaplains has been overlooked. The purpose of this study was to evaluate the perceptions of nurses regarding chaplain involvement in pain management.

Mining echocardiography workflows for disease discriminative patterns.

Objective: To provide quick diagnostic insights to medical practitioners into echocardiograms by only analyzing the echocardiogram workflows (defined as the sequence of modalities examined).

Methods: We define a dictionary of workflows, called subflows, which are commonly encountered in echocardiography workflows but are mutually exclusive. We represent each workflow as a mixture of dictionary subflows and learn discriminative models for various cardiac diseases using Support Vector Machines.

Expression of the high mobility group A family member p8 is essential to maintaining tumorigenic potential by promoting cell cycle dysregulation in LbetaT2 cells.

The mechanism by which the HMGA protein p8 facilitates tumorigenesis may be cell cycle dysregulation. Control- (C) LbetaT2 cells, which express p8, form tumors at a rate five-times faster than p8-knockdown (p8-KD)-LbetaT2 cells. In association with this heightened tumorigenic potential, p8-expressing C-LbetaT2 cells avoid G(0)/G(1) arrest and become genetically unstable while p8-KD-LbetaT2 cells arrest in G(0)/G(1), become senescent upon overgrowth, and maintain a diploid population.

Dominant-negative histone H3 lysine 27 mutant derepresses silenced tumor suppressor genes and reverses the drug-resistant phenotype in cancer cells.

Histone modifications and DNA methylation are epigenetic phenomena that play a critical role in many neoplastic processes, including silencing of tumor suppressor genes. One such histone modification, particularly at H3 and H4, is methylation at specific lysine (K) residues. Whereas histone methylation of H3-K9 has been linked to DNA methylation and aberrant gene silencing in cancer cells, no such studies of H3-K27 have been reported.