Publications by authors named "K Boman"
Background: Providing analgesia and sedation is an essential component of caring for many mechanically ventilated patients. The selection of analgesic and sedative medications during the COVID-19 pandemic, and the impact of these sedation practices on patient outcomes, remain incompletely characterized.
Research Question: What were the hospital patterns of analgesic and sedative use for patients with COVID-19 who received mechanical ventilation (MV), and what differences in clinical patient outcomes were observed across prevailing sedation practices?
Study Design And Methods: We conducted an observational cohort study of hospitalized adults who received MV for COVID-19 from February 2020 through April 2021 within the Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study (VIRUS) COVID-19 Registry.
Article Synopsis
- Tafamidis has been shown to improve survival rates in patients with transthyretin amyloid cardiomyopathy (ATTR-CM), but its specific impact on cardiac function was unclear, prompting further investigation.
- The study analyzed data from the ATTR-ACT clinical trial, involving 436 patients with ATTR-CM, to compare cardiac function measures over 30 months between those receiving tafamidis and a placebo.
- Results indicated that patients treated with tafamidis experienced less deterioration in key cardiac function metrics, suggesting a potential benefit of the drug in managing cardiac issues related to ATTR-CM.
Article Synopsis
- Manual data extraction from electronic health records is resource-intensive, and automating this process can alleviate burdens and enhance research capabilities.
- The study assesses the effectiveness of automated data extraction in a large cohort of adult COVID-19 patients, comparing it with traditional manual methods.
- Results show that automated extraction achieves nearly perfect agreement for most categorical variables and very high correlations for continuous variables, indicating its reliability and feasibility.
Background: Better delineation of COVID-19 presentations in different climatological conditions might assist with prompt diagnosis and isolation of patients.
Objectives: To study the association of latitude and altitude with COVID-19 symptomatology.
Methods: This observational cohort study included 12267 adult COVID-19 patients hospitalized between 03/2020 and 01/2021 at 181 hospitals in 24 countries within the SCCM Discovery VIRUS: COVID-19 Registry.
Objectives: To describe incidence and risk factors of loss of previous independent living through nonhome discharge or discharge home with health assistance in survivors of intensive care unit (ICU) admission for coronavirus disease 2019 (COVID-19).
Design: Multicenter observational study including patients admitted to the ICU from January 2020 till June 30, 2021.
Hypothesis: We hypothesized that there is a high risk of nonhome discharge in patients surviving ICU admission due to COVID-19.