Publications by authors named "K Bliznakova"

Background: The rapid advancement of medical technologies presents significant challenges for researchers and practitioners. While traditional clinical trials remain the gold standard, they are often limited by high costs, lengthy durations, and ethical constraints. In contrast, in-silico trials and digital twins have emerged not only as efficient and ethical alternatives but also as a complementary technology that can extend beyond classical trials to predict and design new strategies.

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This study investigates the feasibility of employing an in-house-developed physical phantom dedicated to the weekly quality control testing of radiographic systems, performed by radiographers. For this purpose, a 3D phantom was fabricated, featuring test objects, including a model representing a lesion. Alongside this phantom, a commercial phantom, specifically, IBA's Primus L, was utilized.

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Article Synopsis
  • Diabetic retinopathy (DR) is a significant cause of vision loss in working-age individuals, particularly in Bulgaria, where a study aimed to assess its prevalence among diabetic patients.
  • The study examined nearly 600 diabetic patients in Varna from January 2022 to January 2023, finding that 39.9% had some form of DR, with higher rates in Type 1 diabetes patients and those on insulin treatment.
  • The results highlight the urgent need for a national screening program to address DR, leveraging technology to improve early detection and treatment, especially in rural areas.
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This submission comprises the proceedings of the 1st Virtual Imaging Trials in Medicine conference, organized by Duke University on April 22-24, 2024. The listed authors serve as the program directors for this conference. The VITM conference is a pioneering summit uniting experts from academia, industry and government in the fields of medical imaging and therapy to explore the transformative potential of in silico virtual trials and digital twins in revolutionizing healthcare.

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Background: Contrast-enhanced mammography is one of the new emerging imaging techniques used for detecting breast tissue lesions. Optimization of imaging protocols and reconstruction techniques for this modality, however, requires the involvement of physical phantoms. Their development is related to the use of radiocontrast agents.

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