Besides various infectious and inflammatory complications, recent studies also indicated the significance of NLRP3 inflammasome in cancer progression and therapy. NLRP3-mediated immune response and pyroptosis could be helpful or harmful in the progression of cancer, and also depend on the nature of the tumor microenvironment. The activation of NLRP3 inflammasome could increase immune surveillance and the efficacy of immunotherapy.
View Article and Find Full Text PDFIntroduction: Guns were one of the leading causes of death in children and youth aged 0-24 years in the U.S. over the last decade, with large variations by sex, race, region, and income.
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