Programmes to support transitions in care for children and youth with complex care needs and their families: a scoping review protocol.

Introduction: Children and youth with complex care needs (CCNs) and their families experience many care transitions over their lifespan and are consequently vulnerable to the discontinuity or gaps in care that can occur during these transitions. Transitional care programmes, broadly defined as one or more intervention(s) or service(s) that aim to improve continuity of care, are increasingly being developed to address transitions in care for children and youth with CCNs. However, this literature has not yet been systematically examined at a comprehensive level.

Aspirin use among adults aged 40 and older in the United States: results of a national survey.

Background: Aspirin is effective for the primary and secondary prevention of cardiovascular events, but its use has been suboptimal.

Methods: Investigators performed a nationally representative Internet-based survey of U.S.

Changes in electrophysiological activity in the accessory olfactory bulb and medial amygdala associated with mate recognition in mice.

The ability of female mice to recognize their mate's pheromonal identity is critical for the maintenance of their pregnancy and is hypothesized to involve increases in the inhibitory control of mitral/tufted projection neurons in the accessory olfactory bulb. Local field potential recordings from this region of freely behaving female mice showed oscillating neural activity over a wide range of frequencies, which was affected by chemosensory input and prior experience. Mating caused lasting increases in the baseline neural activity in the accessory olfactory bulb, with large increases in the amplitude of local field potential oscillations across a range of frequencies.

Release of homocysteic acid from rat thalamus following stimulation of somatosensory afferents in vivo: feasibility of glial participation in synaptic transmission.

The sulphur-containing amino acid homocysteic acid (HCA) is present in and released in vitro from nervous tissue and is a potent neuronal excitant, predominantly activating N-methyl-d-aspartate (NMDA) receptors. However, HCA is localised not in neurones but in glial cells [Eur J Neurosci 3 (1991) 1370], and we have shown that it is released from astrocytes in culture upon glutamate receptor activation [Neuroscience 124 (2004) 377]. We now report the in vivo release of HCA from ventrobasal (VB) thalamus following natural stimulation of somatosensory afferents arising from the facial vibrissae of the rat.

The effect of changing practice on fall prevention in a rehabilitative hospital: the Hospital Injury Prevention Study.

Objectives: To determine whether a change in practice to introduce a multidisciplinary fall-prevention program can reduce falls and injury in nonacute patients in a rehabilitation hospital.

Design: A quasi-experimental study.

Setting: Three geriatric wards with a similar design, equipment, staffing levels, and skill mix.