Spatiotemporal distribution of proliferation, proapoptotic and antiapoptotic factors in the early human limb development.

Involvement of proliferation and apoptosis in the human limb development was analyzed electronmicroscopically and immunohistochemically in histological sections of 8 human embryos, 4(th) -10(th) week old, using apoptotic (caspase-3, AIF, BAX), anti-apoptotic (Bcl-2) and proliferation (Ki-67) markers, and TUNEL method. The data were analyzed by Mann-Whitney test, Kruskal-Wallis and Dunn's post hoc test. Initially, developing human limbs consisted of mesenchymal core and surface ectoderm with apical ectodermal ridge (AER).

Computer representation of osteosynthesis stability in locking plates used for the treatment of osteoporotic proximal humerus fractures.

Background: Proximal humerus fractures are represented as 4-5% of all fractures, with incidence notably growing with age. Since surgical internal fixation in treatment of proximal humeral fractures is used, fractures of osteoporotic bone and choice of plate for their osteosynthesis represent particular problem. The aim of the study was to test two locking plates: Philos plate with locking screws with determinated direction, and Arthrex plate with poliaxial locking screws, using the finite element method.

Peutz-Jeghers syndrome complicated with intussusception: enteroscopic polyps resections through laparotomy.

Peutz-Jeghers syndrome is an autosomal dominant inherited disorder characterized by intestinal hamartomatous polyps in association with mucocutaneous pigmentations. Here we present a case of a 30-year-old woman who was hospitalized and underwent diagnostic procedures because of crampy abdominal pain. Physical examination on admission revealed pigmented spots around lips and on the oral mucosa.

Subbrachial approach to humeral shaft fractures: new surgical technique and retrospective case series study.

Background: There are few surgical approaches for treating humeral shaft fractures. Here we present our results using a subbrachial approach.

Methods: We conducted a retrospective case series involving patients who had surgery for a humeral shaft fracture between January 1994 and January 2008.

Undergraduate design projects for assistive technology needs: assisted fishing.

In 2010 the University of Wyoming, College of Engineering and Applied Science was funded for a five year increment of the National Science Foundation’s Research to Aid Persons with Disabilities. This program provides a vital link between challenged individuals who require custom assistive technology devices with senior capstone design students who require challenging, meaningful projects. The program also provides education for our next generation of engineers on the needs of all individuals.