Publications by authors named "K Bickhardt"

The effects of a single oral application of D-penicillamine (DPA, mean dosage 28 mg/kg body weight) on urinary copper (Cu) excretion and general renal function in six high-Cu supplemented sheep (Cu intake of 3.7 mg/day per kg body weight for 84 days) and four controls (Cu intake of 0.16 mg/day per kg body weight) were investigated to quantify induced cupruresis and the therapeutic effect of DPA as a decoppering agent.

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Fourteen castrated male sheep of two breeds, the Mutton Merino (MMB) and Blackhead Suffolk cross breed (BSC), were exposed to an oral copper (Cu) intake of 3.7 mg/day per kg body weight for 84 days (high Cu group, HCu), and 11 castrated male sheep received a daily oral Cu intake of 0.16 mg/day per kg body weight (controls).

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A review is given about the clinical symptoms, pathogenesis and aetiology of the porcine stress syndrome, furthermore aspects of animal welfare are discussed. The current breeding programmes of pig industry in Germany in many cases include animals with a mutation of the ryanodine-receptor (RYR-1)-gene--homozygous or heterozygous. This situation is the result of an intensive breeding of pigs during the last decades with the intention of increased lean carcass content and corresponding proceeds.

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Haematological and biochemical examinations were carried out in 284 clinically healthy lambs aged from birth to nine month. The 122 male and 164 female animals belonged to the following breeds: German blackheaded mutton sheep (n = 114), Merino (n = 21), Frisian milksheep (n = 98), Texel (n = 31), Bentheimer landrace (n = 16) and Leine sheep (n = 5). The lambs were selected from a larger number of probationers by use of outlier tests.

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In a prospective study from 1991-1998 plasma concentrations of alpha-Tocopherole (VitE) and Selenium (Se) were analysed in 125 sheep and 32 goats with generalised motor disturbances or elevated plasma-activities of Creatine-Kinase (CK). VitE-values < 1.0 mg/l and Se-values < 0.

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