A novel tape-free sample preparation method for human osteochondral cryosections for high throughput hyperspectral imaging.

Understanding the osteochondral junction, where non-mineralised cartilage and mineralised bone converge, is crucial for joint health. Current sample preparation techniques are insufficient for detailed spatial hyperspectral imaging analysis. Using the enhanced Kawamoto method, we used the super cryo embedding medium's temperature-dependent properties to transfer high-quality tissue samples onto slides for spatial imaging analysis.

Terahertz imaging of human skin: Toward detection of abnormal skin pathologies.

Terahertz (THz) imaging has long held promise for skin cancer detection but has been hampered by the lack of practical technological implementation. In this article, we introduce a technique for discriminating several skin pathologies using a coherent THz confocal system based on a THz quantum cascade laser. High resolution THz images (with diffraction limited to the order of 100 m) of several different lesion types were acquired and compared against one another using the amplitude and phase values.

Imaging elastic waves in solids: how to use laser feedback interferometry to visualize them.

The use of ultrasonic elastic waves is a well established technique for non-destructive testing of materials and structures, in particular to exploit the interaction of waves with structural features to detect and characterize defects. Optical methods offer the advantage of visualising the distribution of elastic waves in a non-contact manner without disturbing the elastic wave. In this work we propose a laser feedback interferometry (LFI) based system as a cost effective, non-contact, alternative to a well established laser Doppler vibrometer technique.

Coherent terahertz laser feedback interferometry for hydration sensing in leaves.

The response of terahertz to the presence of water content makes it an ideal analytical tool for hydration monitoring in agricultural applications. This study reports on the feasibility of terahertz sensing for monitoring the hydration level of freshly harvested leaves of Celtis sinensis by employing a imaging platform based on quantum cascade lasers and laser feedback interferometry. The imaging platform produces wide angle high resolution terahertz amplitude and phase images of the leaves at high frame rates allowing monitoring of dynamic water transport and other changes across the whole leaf.