Bumblebee Abundance in Species-Rich Grasslands in Southern Sweden Decreases with Increasing Amount of Arable Land at a Landscape Level.

Conservation of bumblebee populations is essential because of their role as pollinators. Declines in bumblebee abundance have been documented in recent decades, mostly attributed to agricultural intensification, landscape simplification and loss of semi-natural grasslands. In this study, we investigated the effects of landscape composition on bumblebee abundance at different spatial scales in 476 semi-natural grassland sites in southern Sweden.

Testing a Family Conflict Intervention for Parents and Typically Developing Adolescent Siblings of Individuals with Intellectual and/or Developmental Disabilities.

Parents and typically developing (TD) youth siblings of individuals with intellectual and/or developmental disabilities (IDD) often experience greater caregiving burden, stress, and hardships in family functioning. They are at increased risk of family conflict and youth adjustment problems when TD siblings are adolescents since they need to balance caregiving responsibilities and various changes that naturally occur during adolescence. However, there is a lack of intervention research on parents and TD adolescent siblings that focuses on family conflict and family-wide participation.

Targeting GOF p53 and c-MYC through LZK Inhibition or Degradation Suppresses Head and Neck Tumor Growth.

The worldwide frequency of head and neck squamous cell carcinoma (HNSCC) is approximately 800,000 new cases, with 430,000 deaths annually. We determined that LZK (encoded by ) is a therapeutic target in HNSCC and showed that inhibition with small molecule inhibitors decreases the viability of HNSCC cells with amplified . A drug-resistant mutant of LZK blocks decreases in cell viability due to LZK inhibition, indicating on-target activity by two separate small molecules.

Unscheduled home consultations by registered nurses may reduce acute clinic visits.

Background: To effectively utilize available healthcare resources, integrated care models are recommended. According to such model's, registered nurses have the potential to increase patient access to health care services and alleviate organizational workload. Studies on acute home consultation assessments by registered nurses are sparse.