[Activity of alpha-amylase in serum and urine of pregnant women with diabetes mellitus type I].

The investigations covered 33 women in the III trimester of pregnancy with diagnosed, insulin-dependent diabetes mellitus, and 108 healthy women in the control group. The alpha-amylase activity was measured in the blood-serum and urine samples using the Caravay technique. An increased activity was demonstrated in the blood-serum samples in the examined group.

[Kidney function in pregnant women with hypertension in the course of chronic kidney disease].

In 53 pregnant patients in the III trimester of pregnancy kidney function investigations were carried. The group consisted of 23 patients with chronic kidney diseases with superimposed arterial hypertension (examined group) and of 30 healthy pregnant women (control group). In the examined group an increase of blood-serum urea, uric acid and creatinine concentrations were demonstrated.

[Kidney function in pregnant women with primary arterial hypertension].

Investigations covered 64 women in the III trimester of pregnancy. In this group 34 were with diagnosed primary arterial hypertension (examined group), and 30 were apparently healthy (control group). In both groups the blood serum concentrations of creatinine, urea, uric acid and electrolytes were determined.

[Placental lactogen and estrogens in the amniotic fluid in normal pregnancy and in pregnancy complicated by hypertension in relation to the state of the newborn].

The study was carried out in 45 samples of amniotic fluid taken by amniocentesis from 21 hypertensive mothers (study group) and 24 healthy mothers (control group). In these samples the concentrations were determined of total oestrogens and human placental lactogen. In the evaluation of the state of the newborns the following was considered: 1) length and body weight, 2) status in the 1st minute of life (Apgar score).

[Various biochemical functions of the renal tubules and glomeruli in women during normal pregnancy and the puerperium].

The study was carried out in 194 healthy women, including 50 non-pregnant, 31 pregnant in the 1st trimester, 32 in the 2nd and 30 in the 3rd trimester, and 51 in the 3rd day of puerperium. Their age was 19-43 years, they gave no history of renal disease nor urinary tract disease. The biochemical tests evaluating the function of renal tubules and glomeruli were done in 24-hour urine: 1) 24-hour urine volume, 2) NH4+, 3) H+, 4) K+ and 5) Na+ ions.