Studying power-grid synchronization with incremental refinement of model heterogeneity.

The dynamics of electric power systems are widely studied through the phase synchronization of oscillators, typically with the use of the Kuramoto equation. While there are numerous well-known order parameters to characterize these dynamics, shortcoming of these metrics are also recognized. To capture all transitions from phase disordered states over phase locking to fully synchronized systems, new metrics were proposed and demonstrated on homogeneous models.

The cerebral blood flow response to neuroactivation is reduced in cognitively normal men with β-amyloid accumulation.

Background: Accumulation of β-amyloid (Aβ) in the brain is a hallmark of Alzheimer's Disease (AD). Cerebral deposition of Aβ initiates deteriorating pathways which eventually can lead to AD. However, the exact mechanisms are not known.

Cognitive aging and reserve factors in the Metropolit 1953 Danish male cohort.

Identifying early predictors of cognitive decline and at-risk individuals is essential for timely intervention and prevention of dementia. This study aimed to detect neurobiological changes and factors related to cognitive performance in the Metropolit 1953 Danish male birth cohort. We analyzed data from 582 participants, aged 57-68 years, using machine learning techniques to group cognitive trajectories into four clusters differentiating high- and low-performing groups.

Early cerebral amyloid-β accumulation and hypermetabolism are associated with subtle cognitive deficits before accelerated cerebral atrophy.

Aims: Alzheimer's disease (AD) is characterized by the accumulation of amyloid beta (Aβ) in the brain. The deposition of Aβ is believed to initiate a detrimental cascade, including cerebral hypometabolism, accelerated brain atrophy, and cognitive problems-ultimately resulting in AD. However, the timing and causality of the cascade resulting in AD are not yet fully established.

[Not Available].

This review focuses on ageing and sleep. A key focus in aging is to improve senescence by extending good health, optimal cognitive function, and medical and social assistance into later life. Given that one third of the human lifespan is spent sleeping, the importance of maintaining deep, stable, and consistent sleep is self-evident for the good life quality expected and optimal daytime functioning, which the aging process always curtails.