pH-responsive supramolecular switch of a rationally designed dipyrroethene-based chromophore.

Herein, we present a strategy to access a novel class of pH-responsive, dual-state emissive (DSE), highly fluorescent pyrrole-based chromophores diformylation of dipyrroethenes (DPE) followed by condensation with various aniline derivatives. The DPE-based chromophores exhibit a large Stokes shift and maintain good fluorescence quantum yields. Remarkably, these chromophores demonstrate reversible colourimetric changes and a fluorometric 'on-off-on' switch in response to pH variations.

Synthesis, structure, and spectral and electrochemical properties of new visible to NIR absorbing 3-pyrrolyl BODIPY derivatives.

We report the synthesis, characterization, and studies of novel 3-pyrrolyl BODIPY-based Schiff base products 3-6 and 3-pyrrolyl BODIPY-based benzo[]thiazol-2-yl derivatives 7-8. The Schiff base compounds 3-6 were synthesized condensation of α-formyl 3-pyrrolyl BODIPY with various amine derivatives, while the Knoevenagel condensation products 7-8 were obtained by reacting α-formyl 3-pyrrolyl BODIPY with 2-(benzo[]thiazol-2-yl) acetonitrile and bis(benzo[]thiazol-2-yl) methane, respectively. The compounds were thoroughly characterized by using HR-MS, 1D and 2D NMR spectroscopy, and X-ray crystallography for two compounds.

Seaweed-Derived Bioactive Compounds: Potent Modulators in Breast Cancer Therapy.

Cancer remains a major global health concern, with breast cancer being particularly challenging. To address this, new therapeutic strategies are being explored, including natural alternatives. Seaweeds, rich in bioactive compounds, have gained attention for their therapeutic potential.

Substituted thiourea incorporated rhodamine-based chemosensors for selective detection of aluminium ions.

Various metal ions' contemporary utility, biological essence and environmental impact have stimulated their selective and sensitive detection, particularly when present in traces. In this context, methodological explorations relying on structural and functional modulations of prime components and interactive parameters have been pivotal in developing chemosensors for selective detection of such metal ionic inputs. In this investigation, three thiourea-incorporated rhodamine B derivatives varying in their substituent modified covalent architectures were synthesized, and their photophysical signalling responses were monitored in the presence of different metal ions.