Factors associated with equine shedding of multi-drug-resistant Salmonella enterica and its impact on health outcomes.

Background: Salmonella enterica is an important cause of healthcare-associated infections in veterinary hospitals - with outbreaks of multi-drug resistant (MDR) Salmonella among equine cases resulting in high case fatality rates and substantial financial cost.

Objectives: Study objectives were to 1) investigate factors associated with shedding of MDR-Salmonella enterica and 2) evaluate the effect shedding may have on health outcomes of previously hospitalised horses and their stablemates.

Study Design: Retrospective case-control study with prospective cohort study.

Filiform polyposis of the colon in chronic inflammatory bowel disease (so-called giant inflammatory polyps).

On the basis of 3 of our own cases, we describe unusually intense forms of filiform polyposis and local giant polyposis as a consequence of chronic inflammatory bowel disease. The patients are: A 52-year-old woman who for 7 years has been known to have Crohn's disease (CD); a 55-year-old man who for 14 years has been known to have chronic inflammatory bowel disease, which was first thought to have been ulcerative colitis, but, as a result of the findings on the subtotal colectomy specimen, had to be classified as Crohn's disease or colitis indeterminate; and a 53-year-old woman known to have had ulcerative colitis for 37 years. From the literature on the subject, we drew up a chronological list of a total of 43 cases with similar or completely identical findings.

[Combined regional chemotherapy and radiotherapy of liver metastases].

In an attempt to treat patients with non-resectable liver metastases more effectively, hepatic arterial chemotherapy (12 g 5-FU in 3 weeks) was combined with simultaneous whole liver irradiation (8 Gy every week, total dose of 24 Gy). 54 of the 64 patients receiving this treatment had liver metastases from colorectal carcinoma. The objective response rate, judged by CAT scan, was nearly 60%.

[The esophageal cyst--a rare congenital abnormality].

Esophageal cysts are among the embryonic malformations of the gastrointestinal tract. They develop from persisting diverticulum-like evaginations of the embryonic esophagus. The esophageal cyst is usually asymptomatic and is frequently diagnosed as an incidental finding.