Publications by authors named "K Baksaas-Aasen"
Article Synopsis
- Trauma hemorrhage leads to a serious coagulopathy with high mortality rates, prompting the ITACTIC trial to compare treatment strategies based on conventional tests versus viscoelastic assays for better outcomes.
- Although the viscoelastic group was more likely to receive goal-directed treatment (76% vs. 47%), only about half of the patients received this treatment overall, and just 20% of them corrected their coagulopathy.
- The study highlighted that many bleeding trauma patients did not receive the necessary goal-directed care, revealing a potential gap in effective treatment strategies.
Background: After 15 years of damage control resuscitation (DCR), studies still report high mortality rates for critically bleeding trauma patients. Adherence to massive hemorrhage protocols (MHPs) based on a 1:1:1 ratio of plasma, platelets, and red blood cells (RBCs) as part of DCR has been shown to improve outcomes. We wanted to assess MHP use in the early (6 hours from admission), critical phase of DCR and its impact on mortality.
View Article and Find Full Text PDFSeverely injured trauma patients are often coagulopathic and early hemostatic resuscitation is essential. Previous studies have revealed linear relationships between thrombelastography (TEG) five- and ten-min amplitudes (A5 and A10), and maximum amplitude (MA), using TEG 5000 technology. We aimed to investigate the performance of A5 and A10 in predicting low MA in severely injured trauma patients and identify optimal cut-off values for hemostatic intervention based on early amplitudes, using the cartridge-based TEG 6s technology.
View Article and Find Full Text PDFBackground: In line with international trends, initial treatment of trauma patients has changed substantially over the last two decades. Although trauma is the leading cause of death and disability in children globally, in-hospital pediatric trauma related mortality is expected to be low in a mature trauma system. To evaluate the performance of a major Scandinavian trauma center we assessed treatment strategies and outcomes in all pediatric trauma patients over a 16-year period.
View Article and Find Full Text PDFPurpose: Contemporary trauma resuscitation prioritizes control of bleeding and uses major haemorrhage protocols (MHPs) to prevent and treat coagulopathy. We aimed to determine whether augmenting MHPs with Viscoelastic Haemostatic Assays (VHA) would improve outcomes compared to Conventional Coagulation Tests (CCTs).
Methods: This was a multi-centre, randomized controlled trial comparing outcomes in trauma patients who received empiric MHPs, augmented by either VHA or CCT-guided interventions.