Publications by authors named "K Badu"

Background: Malaria has been described as a disease of poverty, affecting the poorest populations typically living in rural areas. As hitherto rural areas transition into semi-urban environments, this study investigated the prevalence of falciparum malaria and associated risk factors in two rapidly urbanizing districts in the Ashanti Region of Ghana.

Methods: A cross-sectional, hospital-based study was conducted at Agona and Mankranso Government Hospitals located within the Sekyere South and Ahafo Ano Southwest districts respectively, in the Ashanti Region of Ghana.

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Background: Reactive case detection (RCD) aims to reduce malaria transmission stemming from asymptomatic carriers. Symptomatic individuals diagnosed with malaria at a health centre are followed to their households, where members of the index case and neighbouring households are tested and treated for malaria. An RCD programme was tested in the Ashanti region of Ghana in order to study diagnostic accuracy in the hospital and household settings, assess the prevalence of subclinical infections and possible clustering in index case households, and identify operational challenges for future RCD programmes.

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Article Synopsis
  • Accurate diagnosis and timely treatment of malaria are essential, with 449 samples screened for Plasmodium falciparum infection using various methods, including microscopy, qPCR, and three rapid diagnostic tests (RDTs).
  • The results showed that 45.7% of individuals tested positive for P. falciparum via qPCR, with the sensitivity of the RDTs significantly higher than microscopy, especially when sample parasite densities exceeded 20 parasites/μL.
  • The Biocredit and NxTek RDTs demonstrated similar diagnostic effectiveness, outperforming microscopy, while all three RDTs maintained high specificity of over 95%.
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Global artificial intelligence (AI) governance must prioritize equity, embrace a decolonial mindset, and provide the Global South countries the authority to spearhead solution creation. Decolonization is crucial for dismantling Western-centric cognitive frameworks and mitigating biases. Integrating a decolonial approach to AI governance involves recognizing persistent colonial repercussions, leading to biases in AI solutions and disparities in AI access based on gender, race, geography, income and societal factors.

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Sensitive and accurate malaria diagnosis is required for case management to accelerate control efforts. Diagnosis is particularly challenging where multiple Plasmodium species are endemic, and where P. falciparum hrp2/3 deletions are frequent.

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