Publications by authors named "K Bader"
A 2012 review of therapeutic ultrasound was published to educate researchers and physicians on potential applications and concerns for unintended bioeffects (doi: 10.7863/jum.2012.
View Article and Find Full Text PDFArticle Synopsis
- Rhino-orbital-cerebral mucormycosis is a severe fungal infection primarily affecting immunocompromised individuals, known for its ability to invade blood vessels and cause tissue death.
- A case study discusses a 59-year-old man with poorly controlled diabetes who presented with neurological symptoms that were initially misdiagnosed and worsened with corticosteroid treatment, leading to a rapid decline in his condition.
- The case emphasizes the urgent need for early diagnosis and treatment of mucormycosis to prevent severe complications and highlights the dangers of using corticosteroids without identifying underlying fungal infections.
Background: Clinical data are usually analyzed with the assumption that knowledge gathered from group averages applies to the individual. Doing so potentially obscures patients with meaningfully different trajectories of therapeutic change. Needed are "idionomic" methods that first examine idiographic patterns before nomothetic generalizations are made.
View Article and Find Full Text PDFBackground: To date, there is no consensus on how to standardize the assessment of ototoxicity in serial measurements. For the diagnosis of damage to the cochlear amplifier, measurement methods are required that have the highest possible test-retest reliability and validity for detecting persistent damage. Estimated distortion-product thresholds (L) based on short-pulse distortion-product otoacoustic emission (DPOAE) level maps use individually optimal DPOAE stimulus levels and allow reliable quantitative estimation of cochlea-related hearing loss.
View Article and Find Full Text PDFObjectives: To date, there is no international standard on how to use distortion-product otoacoustic emissions (DPOAEs) in serial measurements to accurately detect changes in the function of the cochlear amplifier due, for example, to ototoxic therapies, occupational noise, or the development of regenerative therapies. The use of clinically established standard DPOAE protocols for serial monitoring programs appears to be hampered by multiple factors, including probe placement and calibration effects, signal-processing complexities associated with multiple sites of emission generation as well as suboptimal selection of stimulus parameters.
Design: Pulsed DPOAEs were measured seven times within 3 months for f2 = 1 to 14 kHz and L2 = 25 to 80 dB SPL in 20 ears of 10 healthy participants with normal hearing (mean age = 32.