Consumer views about aging-in-place.

Background: Supporting older people's choices to live safely and independently in the community (age-in-place) can maximize their quality of life and minimize unnecessary hospitalizations and residential care placement. Little is known of the views of older people about the aging-in-place process, and how they approach and prioritize the support they require to live in the community accommodation of their choice.

Purpose: To explore and synthesize the experiences and perspectives of older people planning for and experiencing aging-in-place.

Exercise parameters in the management of breast cancer: a systematic review of randomized controlled trials.

Aim: Previous systematic reviews have examined the efficacy of exercise in improving the quality of life for patients with, and survivors of, breast cancer. This review sets out to determine the parameters of exercise programmes used in randomized controlled trials.

Methods: A systematic review of randomized controlled trials was conducted.

Acute whiplash associated disorders (WAD).

Background: Whiplash-associated disorder (WAD) is the term given for the collection of symptoms affecting the neck that are triggered by an accident with an acceleration-deceleration mechanism such as a motor vehicle accident. The incidence of whiplash injury varies greatly between different parts of the world with significant monetary burden on the individual as well as the wider community.

Objective: Which treatments are best for reducing pain and disability experience in acute WADs?

Level Of Evidence: Clinical practice guidelines, systematic reviews, meta-analysis, randomized controlled trials.

Amphotericin B induced abnormalities in human platelets.

Aims-To investigate in vitro the effect of amphotericin B on platelets in order to understand poor platelet recovery in patients receiving platelet transfusions and amphotericin B simultaneously.Methods-Washed platelets were isolated from platelet concentrates and exposed to amphotericin B (4 mug/ml) for one hour. Platelet function was assessed by aggregation response to thrombin (0-0.

Adhesion of platelets to chemotactically responsive and non-responsive neutrophils.

Aims-To investigate the heterotypic adhesion of unactivated platelets to chemotactically responsive (migrated) and non-responsive (non-migrated) polymorphonuclear neutrophils (PMN).Methods-Platelets and PMN were isolated from autologous, normal blood. Migrated and non-migrated PMN were separated after N-formylmethionyl-leucylphenylalanine (FMLP) stimulation.