Publications by authors named "K B Gloer"
Article Synopsis
- Heparin combined with GP IIb/IIIa inhibitors is effective for acute coronary syndrome (ACS) patients undergoing PCI, but bivalirudin has emerged as a strong alternative.
- In a study of 891 PCI patients with ACS, those on bivalirudin experienced better angiographic outcomes compared to those on heparin, despite fewer using adjunctive inhibitors.
- No significant differences in bleeding events or major adverse cardiac events were noted between the two groups, suggesting that bivalirudin could be as effective and safe as heparin in this high-risk setting.
Objectives: To test the effectiveness of Rheolytic Thrombectomy (RT) and distal protection balloon wires when used synergistically in an in vitro model.
Background: Although effective, currently available technologies may not be individually ideal for fresh clots removal.
Methods: Fourteen, fresh blood samples were placed in 14 plastic tubes and left to clot for 6 h.
A 55-year-old male patient experienced 2 acute neurologic events 3 weeks after orthotopic cardiac transplantation. Transesophageal echocardiography demonstrated a patent foramen ovale in the native portion of the interatrial septum with bidirectional shunting by Doppler and microbubble contrast. The defect was closed successfully with a CardioSeal transcatheter septal closure device.
View Article and Find Full Text PDFThree new p-terphenyls (1-3), a new xanthone derivative (4), and two known fungal metabolites (5 and 6) have been isolated from the sclerotia of Penicillium raistrickii (NRRL 2039). The structures for 3,3"-dihydroxy-6'-desmethylterphenyllin (1); 3'-demethoxy-6'-desmethyl-5'-methoxycandidusin B (2); 6'-desmethylcandidusin B (3); and 1,3,5, 6-tetrahydroxy-8-methylxanthone (4) were determined on the basis of HRMS and NMR data. Although compounds 1 and 4 exhibited mild antiinsectan and antibacterial activity, griseofulvin (5) was responsible for most of the activity of the sclerotial extract in dietary assays against the corn earworm Helicoverpa zea.
View Article and Find Full Text PDFTwo new benzoquinones with antifungal, antibacterial, and cytotoxic activities have been isolated from liquid cultures of the coprophilous fungus Podospora anserina. The structures of anserinones A (1) and B (2) were assigned on the basis of MS and NMR results, and the absolute stereochemistry of 2 was deduced by analysis of 1H-NMR data for its (R)- and (S)-2-phenylbutyryl ester derivatives.
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